Autophagy

MRT68921 HCl View larger

MRT68921 HCl

AT5356

CAS 2070014-87-6

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$31.00

$31.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.95 Total: $1,395.00
150 $16.12 Total: $806.00
125 $18.91 Total: $472.75
110 $22.32 Total: $223.20
15 $26.35 Total: $131.75

Data sheet

Molecular FormulaC25H34N6O
Molecular Weight471.04
CAS Numbers2070014-87-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.CN1CCc2cc(Nc3ncc(C4CC4)c(NCCCNC(=O)C4CCC4)n3)ccc2C1
ReferencesPetherick KJ, et al. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin [mTOR]-dependent autophagy. J Biol Chem. 2015 May 1;290[18] 11376-83.

More info

MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 [IC50s: 2.9 and 1.1 nM, respectively].