Autophagy

ULK-101 View larger

ULK-101

AT5403

CAS 2443816-45-1

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$96.00

$96.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $43.20 Total: $4,320.00
150 $49.92 Total: $2,496.00
125 $58.56 Total: $1,464.00
110 $69.12 Total: $691.20
15 $81.60 Total: $408.00

Data sheet

Molecular FormulaC22H16F4N4OS
Molecular Weight460.45
CAS Numbers2443816-45-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFc1ccc(cc1)-c1cnc2c(cnn2c1)-c1csc(c1)C(=O)N[C@@H](C1CC1)C(F)(F)F
ReferencesMartin KR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018 Oct 26;8 74-84.

More info

ULK-101 is a potent and selective inhibitor of ULK1 (IC50s: 8.330 nM for ULK1ULK2). It can suppress autophagy.