Autophagy

TSPO ligand-1 View larger

TSPO ligand-1

AT73599

CAS 4560-08-1

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC16H10ClNO2
Molecular Weight283.71
CAS Numbers4560-08-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(Cl)C(=O)C=1C=2C=CC=CC2NC1C=3C=CC=CC3
ReferencesTakahashi D, et, al. AUTACs Cargo-Specific Degraders Using Selective Autophagy. Mol Cell. 2019 Dec 5;76[5] 797-810.e10.

More info

TSPO ligand-1 has affinity for peripheral and central benzodiazepine receptors.TSPO ligand-1 is an AUTAC4-binding protein in the transmembrane domain of the outer mitochondrial membrane, which induces mitochondrial autophagy and promotes intracellular mitochondrial regeneration.TSPO ligand-1 is involved in intracellular cholesterol transport, and can be used as a biomarker for brain injury and neurodegeneration. TSPO ligand-1 is involved in intracellular cholesterol transport and can be used as a biomarker for brain damage and neurodegeneration.