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Autophagy

Oxybenzone View larger

Oxybenzone

AT0499

CAS 131-57-7

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Data sheet

Molecular FormulaC14H12O3
Molecular Weight228.24
CAS Numbers131-57-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOC1=CC(O)=C(C=C1)C(=O)C1=CC=CC=C1
ReferencesJannesson L, et al. J Clin Periodontol. 2004, 31[2] 91-4.

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Oxybenzone is a UV filter commonly used in tanning and skin protection agents. It is a derivative of benzophenone and is used as an endocrine disrupting chemical that penetrates the placental and blood-brain barriers. It impairs autophagy, alters epigenetic status and disrupts vitamin X-like receptor signaling in apoptotic neuronal cells.