Activity: Measured in a cell proliferation assay using Balb/C 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.15-0.75 ng/mL.
Activity: (1) Measured by its ability to bind human IGFBP4-His (Cat:10967-H08H) in a functional ELISA. (2) Measured by its ability to bind mouse IGFBP4-His (Cat:50250-M08H) in a functional ELISA. (3) Measured by its ability to bind Cynomolgus IGFBP1-His (Cat:90085-C08H) in a functional ELISA.(continued below)