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View larger Tetrahydropalmatine Bulk
AOB0852
CAS 10097-84-4
Chemical Name: Rotundine; L-Tetrahydropalmatine; (-)-Tetrahydropalmatine; (S)-Tetrahydropalmatine; Caseanine; (13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
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Data sheet
| Molecular Formula | C21H25NO4 |
| Molecular Weight | 355.43 |
| CAS Numbers | 10097-84-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 99% (HPLC) |
| Synonym | Tetrahydropalmatine; Rotundine; L-Tetrahydropalmatine; (-)-Tetrahydropalmatine; (S)-Tetrahydropalmatine; Caseanine; |
| IUPAC/Chemical Name | (13aS)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline |
| InChl Key | AEQDJSLRWYMAQI-KRWDZBQOSA-N |
| InChl Code | 1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m0/s1 |
| SMILES Code | COC1=C(OC)C2=C(C=C1)C[C@]3([H])N(CCC4=C3C=C(OC)C(OC)=C4)C2 |
| References | 1) Zhao Y, Liang A, Zhang Y, Li C, Yi Y, Nilsen OG. Impact of Tetrahydropalmatine on the Pharmacokinetics of Probe Drugs for CYP1A2, 2D6 and 3A Isoenzymes in Beagle Dogs. Phytother Res. 2016 Jun;30(6):906-14. doi: 10.1002/ptr.5608. Epub 2016 Mar 17. Review. PubMed PMID: 26990021. 2) Doosti F, Dashti S, Tabatabai SM, Hosseinzadeh H. Traditional Chinese and Indian medicine in the treatment of opioid-dependence: a review. Avicenna J Phytomed. 2013 Summer;3(3):205-15. Review. PubMed PMID: 25050276; PubMed Central PMCID: PMC4075718. |
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Blocker of voltage-activated L-type calcium channel active potassium channels