Calcium Channel

Carboxyamidotriazole Orotate View larger

Carboxyamidotriazole Orotate

AT14871

CAS 187739-60-2

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$47.00

$47.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.15 Total: $2,115.00
150 $24.44 Total: $1,222.00
125 $28.67 Total: $716.75
110 $33.84 Total: $338.40
15 $39.95 Total: $199.75

Data sheet

Molecular FormulaC22H16Cl3N7O6
Molecular Weight580.76
CAS Numbers187739-60-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(=O)c1cc(=O)[nH]c(=O)[nH]1.NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N
ReferencesCorrado C, et al. Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis. PLoS One. 2012;7[8] e42310.

More info

Carboxyamidotriazole Orotate (L-651582 Orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and associated signaling pathways. As the orotate salt form of Carboxyamidotriazole (CAI), it is an orally bioavailable signal transduction inhibitor with in vitro antileukaemic activity, exhibiting anti-tumor, anti-inflammatory, and antiangiogenic effects.