Calcium Channel

KN-92 hydrochloride View larger

KN-92 hydrochloride

AT8543

CAS 1431698-47-3

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$54.00

$54.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $24.30 Total: $2,430.00
150 $28.08 Total: $1,404.00
125 $32.94 Total: $823.50
110 $38.88 Total: $388.80
15 $45.90 Total: $229.50

Data sheet

Molecular FormulaC24H26Cl2N2O3S
Molecular Weight493.45
CAS Numbers1431698-47-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.COc1ccc(cc1)S(=O)(=O)Nc1ccccc1CN(C)CC=Cc1ccc(Cl)cc1
ReferencesRezazadeh S, Claydon TW, Fedida D. et al. KN-93 [2-[N-[2-hydroxyethyl]]-N-[4-methoxybenzenesulfonyl]]amino-N-[4-chlorocinnamyl]-N-methylbenzylamine], a calciumcalmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels. J Pharmacol Exp Ther. 2006 Apr;317[1] 292-9.

More info

KN-92 hydrochloride is an inactive derivative of the selective Ca2+calmodulin-dependent kinase II (CaMKII) inhibitor KN-93, which competitively blocks CaM binding to the kinase with a Ki of 370 nM.