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View larger KN-92 hydrochloride
AT8543
CAS 1431698-47-3
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Data sheet
| Molecular Formula | C24H26Cl2N2O3S |
| Molecular Weight | 493.45 |
| CAS Numbers | 1431698-47-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.COc1ccc(cc1)S(=O)(=O)Nc1ccccc1CN(C)CC=Cc1ccc(Cl)cc1 |
| References | Rezazadeh S, Claydon TW, Fedida D. et al. KN-93 [2-[N-[2-hydroxyethyl]]-N-[4-methoxybenzenesulfonyl]]amino-N-[4-chlorocinnamyl]-N-methylbenzylamine], a calciumcalmodulin-dependent protein kinase II inhibitor, is a direct extracellular blocker of voltage-gated potassium channels. J Pharmacol Exp Ther. 2006 Apr;317[1] 292-9. |
More info
KN-92 hydrochloride is an inactive derivative of the selective Ca2+calmodulin-dependent kinase II (CaMKII) inhibitor KN-93, which competitively blocks CaM binding to the kinase with a Ki of 370 nM.