Cancer Research

Oxaliplatin View larger

Oxaliplatin

AOB6189

CAS: 61825-94-3

 

Chemical Name: Eloxatin; Foloxatine; Eloxatine; [SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-N,N')[ethanedioata(2--)-O,O']platinum

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$11.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $4.95 Total: $495.00
150 $5.72 Total: $286.00
125 $6.71 Total: $167.75
110 $7.92 Total: $79.20
15 $9.35 Total: $46.75

Data sheet

Molecular FormulaC8H14N2O4Pt
Molecular Weight397.29
CAS Numbers61825-94-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Alcohol
Purity98% by HPLC
Synonymdiaminocyclohexane oxalatoplatinum; oxalatoplatin; oxalatoplatinum; US brand name: Eloxatin Foreign brand names: Dacotin; Dacplat; Eloxatine; Abbreviations: 1OHP; LOHP; Code names: JM83; RP54780; SR96669.
IUPAC/Chemical Name[(1R,2R)-cyclohexane-1,2-diamine](ethanedioato-O,O')platinum(II)
InChl KeyZROHGHOFXNOHSO-UHFFFAOYSA-L
InChl CodeInChI=1S/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2
SMILES CodeO=C1[O-][Pt+2]2([O-]C1=O)[NH2]C3CCCCC3[NH2]2
References1) Ye F, Liu Z, Tan A, Liao M, Mo Z, Yang X. XRCC1 and GSTP1 polymorphisms and prognosis of oxaliplatin-based chemotherapy in colorectal cancer: a meta-analysis. Cancer Chemother Pharmacol. 2013 Mar;71(3):733-40. doi: 10.1007/s00280-012-2067-8. Epub 2013 Jan 9. Review. PubMed PMID: 23299794.

2) Leon-Ferre RA, Abu Hejleh TB, Halfdanarson TR. Extravasation of oxaliplatin into the mediastinum: a case report and review of the literature. Clin Adv Hematol Oncol. 2012 Aug;10(8):546-8. Review. PubMed PMID: 23073056.

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Anti-tumor agent with activity against colorectal cancer; cytotoxicity follows the formation of adducts with DNA