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> Cancer Research>BT-11 (Omilancor) dihydrochloride

Cancer Research

BT-11 dihydrochloride View larger

BT-11 (Omilancor) dihydrochloride

AOB16934

CAS: 1912399-75-7

 

Chemical Name: Piperazine-1,4-diylbis((6-(1H-benzo[d]imidazol-2-yl)pyridin-2-yl)methanone) dihydrochloride

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$21.00

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Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
5 $17.85 Total: $89.25
10 $15.12 Total: $151.20
25 $12.81 Total: $320.25
50 $10.92 Total: $546.00
100 $9.45 Total: $945.00

Data sheet

Molecular FormulaC30H26Cl2N8O2
Molecular Weight601.49
CAS Numbers1912399-75-7
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO: ≥ 30 mg/mL
Purity98% by HPLC
SynonymOmilancor; B11
IUPAC/Chemical NamePiperazine-1,4-diylbis((6-(1H-benzo[d]imidazol-2-yl)pyridin-2-yl)methanone) dihydrochloride
SMILES CodeO=C(N1CCN(C(C2=NC(C3=NC4=CC=CC=C4N3)=CC=C2)=O)CC1)C5=NC(C6=NC7=CC=CC=C7N6)=CC=C5
References1) Adria Carbo et al., An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C-Like 2-Based Therapeutic for Inflammatory Bowel Disease, J Med Chem. 2016 Nov 23;59(22):10113-10126. doi: 10.1021/acs.jmedchem.6b00412. Epub 2016 Nov 15.

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Novel Activator of Lanthionine synthetase C-like 2 (LANCL2), Ameliorating Inflammatory Bowel Disease by Enhancing Regulatory T Cell Responses in the Gut, Supporting Regulatory T Cell Stability Through Immunometabolic Mechanisms