Cart 6 Product Products $567.00 (empty)
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1.00 x 1.00mg CB1R Allosteric modulator 3$30.00 -
1.00 x 1.00mg PU-H71$28.00 -
1.00 x 1.00mg USP22-IN-1$34.00 -
1.00 x 1.00mg MD2-TLR4-IN-1$79.00
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Total products (tax excl.) $567.00
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Total (tax excl.) $616.95
Cannabinoid Receptors
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $19.35 | Total: $1,935.00 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 5 | $36.55 | Total: $182.75 |
Data sheet
| Molecular Formula | C21H24BrFN2O2 |
| Molecular Weight | 435.33 |
| CAS Numbers | 2244579-87-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C(=O)C1CCCCCC1)C=2C(=O)N(CC3=CC=C(F)C=C3)C=C(Br)C2C |
| References | Gado F, et al. Identification of the First Synthetic Allosteric Modulator of the CB2 Receptors and Evidence of Its Efficacy for Neuropathic Pain Relief. J Med Chem. 2019;62[1] 276-287. |
More info
CB2R PAM is an orally active cannabinoid type 2 receptor (CB2Rs) positive allosteric modulator that enhances CP 55940 and 2-Arachidonylglycerol-stimulated [35S]GTP?S binding to CB2 receptors without affecting receptor activity in the absence of agonists. CB2R PAM shows anti-injury activity in a mouse model of neuropathic pain.