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Olumacostat Glasaretil
AOB37910
CAS No: 1261491-89-7
Chemical Name: [2-[(2-Ethoxy-2-oxoethyl)-methylamino]-2-oxoethyl] 5-tetradecoxyfuran-2-carboxylate
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $9.45 | Total: $945.00 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 5 | $17.85 | Total: $89.25 |
Data sheet
| Molecular Formula | C26H43NO7 |
| Molecular Weight | 481.63 |
| CAS Numbers | 1261491-89-7 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Olumacostat glasaretil; DRM01B; DRM-01B; DRM 01B. |
| IUPAC/Chemical Name | 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-(tetradecyloxy)furan-2-carboxylate |
| InChl Key | FYJLDICZGDFWKP-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C26H43NO7/c1-4-6-7-8-9-10-11-12-13-14-15-16-19-32-25-18-17-22(34-25)26(30)33-21-23(28)27(3)20-24(29)31-5-2/h17-18H,4-16,19-21H2,1-3H3 |
| SMILES Code | O=C(C1=CC=C(OCCCCCCCCCCCCCC)O1)OCC(N(CC(OCC)=O)C)=O |
| References | 1) Bissonnette R, et al., Olumacostat glasaretil, a novel topical sebum inhibitor, in the treatment of acne vulgaris: A phase IIa, multicenter, randomized, vehicle-controlled study. J Am Acad Dermatol. 2017 Jan;76(1):33-39. doi: 10.1016/j.jaad.2016.08.053. Epub 2016 Oct 28. PubMed 2) Hunt DW, Winters GC, Brownsey RW, Kulpa JE, Gilliland KL, Thiboutot DM, Hofland HE. Inhibition of Sebum Production with the Acetyl Coenzyme A CarboxylaseInhibitor Olumacostat Glasaretil. J Invest Dermatol. 2017 Mar 1. pii:S0022-202X(17)30186-0. doi: 10.1016/j.jid.2016.12.031. [Epub ahead of print]PubMed PMID: 28259683. |
More info
Novel inhibitor of acetyl coenzyme A carboxylase (ACC)