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Gardiquimod
AOB0148
CAS: 1020412-43-4
Chemical Name: 1-[4-Amino-2-(ethylaminomethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $4.05 | Total: $405.00 |
| 1 | 50 | $4.68 | Total: $234.00 |
| 1 | 25 | $5.49 | Total: $137.25 |
| 1 | 10 | $6.48 | Total: $64.80 |
| 1 | 5 | $7.65 | Total: $38.25 |
Data sheet
| Molecular Formula | C17H23N5O |
| Molecular Weight | 313.40 |
| CAS Numbers | 1020412-43-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Gardiquimod |
| IUPAC/Chemical Name | 1-[4-Amino-2-(ethylaminomethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol |
| InChl Key | FHJATBIERQTCTN-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H23N5O/c1-4-19-9-13-21-14-15(22(13)10-17(2,3)23)11-7-5-6-8-12(11)20-16(14)18/h5-8,19,23H,4,9-10H2,1-3H3,(H2,18,20) |
| SMILES Code | CC(O)(C)CN1C(CNCC)=NC2=C1C3=CC=CC=C3N=C2N |
| References | 1) Kim S, Kaiser P, Borowska D, Vervelde L. Synergistic effect of co-stimulation of membrane and endosomal TLRs on chicken innate immune responses. Vet Immunol Immunopathol. 2018 May;199:15-21. 2) Enosi Tuipulotu D, Netzler NE, Lun JH, Mackenzie JM, White PA. TLR7 Agonists Display Potent Antiviral Effects against Norovirus Infection via Innate Stimulation. Antimicrob Agents Chemother. 2018 Apr 26;62(5). pii: e02417-17. |
More info
TLR7 agonist, inducing the activation of NF-B in HEK293 cells expressing human or mouse TLR7