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View larger SM-122
AOB2204
CAS 874270-38-9
Chemical Name: (3S,6S,10aS)-N-Benzhydryl-6-[[(2S)-2-(methylamino)propanoyl]amino]-5-oxo-2,3,6,7,8,9,10,10a-octahydro-1H-pyrrolo[1,2-a]azocine-3-carboxamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $58.65 | Total: $293.25 |
| 1 | 10 | $49.68 | Total: $496.80 |
| 1 | 25 | $42.09 | Total: $1,052.25 |
| 1 | 50 | $35.88 | Total: $1,794.00 |
| 1 | 100 | $31.05 | Total: $3,105.00 |
Data sheet
| Molecular Formula | C28H36N4O3 |
| Molecular Weight | 476.61 |
| CAS Numbers | 874270-38-9 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (3S,6S,10aS)-N-Benzhydryl-6-[[(2S)-2-(methylamino)propanoyl]amino]-5-oxo-2,3,6,7,8,9,10,10a-octahydro-1H-pyrrolo[1,2-a]azocine-3-carboxamide |
| InChl Key | XBTLZUHJBOBKRG-HCUBDLJJSA-N |
| InChl Code | InChI=1S/C28H36N4O3/c1-19(29-2)26(33)30-23-16-10-9-15-22-17-18-24(32(22)28(23)35)27(34)31-25(20-11-5-3-6-12-20)21-13-7-4-8-14-21/h3-8,11-14,19,22-25,29H,9-10,15-18H2,1-2H3,(H,30,33)(H,31,34)/t19-,22-,23-,24-/m0/s1 |
| SMILES Code | CNC(C(=O)NC1CCCCC2N(C1=O)C(CC2)C(=O)NC(c1ccccc1)c1ccccc1)C |
| References | 1) Sunm H., et al Nonpeptidic and Potent Small-Molecule Inhibitors of cIAP-1/2 and XIAP Proteins, J. Med. Chem. 2010, 53, 17, 6361–6367 |
More info
Non-peptidic Smac mimetic, potently binding to XIAP, cIAP-1 and cIAP-2, efficiently inhibiting cell growth, and inducing cell death in a number of cancer cell lines