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Cell Inhibition

EOAI3402143 View larger

EOAI3402143

AOB8093

CAS No: 1699750-95-2


Chemical Name: G9; 2-Cyano-3-(3,6-dichloro-pyridin-2-yl)-N-{1-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-butyl}-acrylamide

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$31.50

$31.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $26.78 Total: $133.88
110 $22.68 Total: $226.80
125 $19.22 Total: $480.38
150 $16.38 Total: $819.00
1100 $14.18 Total: $1,417.50

Data sheet

Molecular FormulaC25H28Cl2N4O3
Molecular Weight503.42
CAS Numbers1699750-95-2
Storage Condition0°C (short term), -20°C (long term), desiccated
Solubility2 mg/mL in DMSO
Purity98% by HPLC
IUPAC/Chemical Name2-Cyano-3-(3,6-dichloro-pyridin-2-yl)-N-{1-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-butyl}-acrylamide
InChl KeyIIKVQQNZHGBYGQ-KNTRCKAVSA-N
InChl CodeInChI=1S/C25H28Cl2N4O3/c1-2-3-22(30-25(32)19(17-28)16-23-21(26)8-9-24(27)29-23)18-4-6-20(7-5-18)34-15-12-31-10-13-33-14-11-31/h4-9,16,22H,2-3,10-15H2,1H3,(H,30,32)/b19-16+
SMILES CodeClC1=C(/C=C(C(NC(CCC)C2=CC=C(OCCN3CCOCC3)C=C2)=O)C#N)N=C(Cl)C=C1.[E]
References1) Potu H, et al. Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway. Oncotarget. 2014 Jul 30;5(14):5559-69.

2) Peterson LF, et al. Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies. Blood. 2015 Jun 4;125(23):3588-97.

3) Pal A, et al. Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth. Neoplasia. 2018 Feb;20(2):152-164.

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