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View larger Mavorixafor
ATQ0174
CAS 558447-26-0
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Data sheet
| Molecular Formula | C21H27N5 |
| Molecular Weight | 349.47 |
| CAS Numbers | 558447-26-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(CC=1NC=2C(N1)=CC=CC2)(CCCCN)[C@@H]3C=4C(CCC3)=CC=CN4 |
| References | Chow LN, et al. Impact of a CXCL12CXCR4 Antagonist in Bleomycin [BLM] Induced Pulmonary Fibrosis and Carbon Tetrachloride [CCl4] Induced Hepatic Fibrosis in Mice. PLoS One. 2016 Mar 21;11[3] e0151765. |
More info
Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM).