Chemokines

Reparixin View larger

Reparixin

AT4163

CAS 266359-83-5

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$41.00

$41.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $18.45 Total: $1,845.00
150 $21.32 Total: $1,066.00
125 $25.01 Total: $625.25
110 $29.52 Total: $295.20
15 $34.85 Total: $174.25

Data sheet

Molecular FormulaC14H21NO3S
Molecular Weight283.39
CAS Numbers266359-83-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)Cc1ccc(cc1)[C@@H](C)C(=O)NS(C)(=O)=O
ReferencesMoriconi A, et al. Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2. J Med Chem. 2007 Aug 23;50[17] 3984-4002.

More info

Reparixin (Repertaxin) is a potent inhibitor of both CXCL8 receptors CXCR12, it inhibits weakly CXCR2-mediated cell migration (IC50=100 nM), whereas it strongly blocks CXCR1-mediated chemotaxis (IC50=1 nM).