Chemokines

Danirixin View larger

Danirixin

AT5193

CAS 954126-98-8

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$48.00

$48.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.60 Total: $2,160.00
150 $24.96 Total: $1,248.00
125 $29.28 Total: $732.00
110 $34.56 Total: $345.60
15 $40.80 Total: $204.00

Data sheet

Molecular FormulaC19H21ClFN3O4S
Molecular Weight441.9
CAS Numbers954126-98-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(c1O)S(=O)(=O)[C@H]1CCCNC1
ReferencesMiller BE, et al. The pharmacokinetics and pharmacodynamics of danirixin [GSK1325756]--a selective CXCR2 antagonist --in healthy adult subjects. BMC Pharmacol Toxicol. 2015 Jun 20;16 18.

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Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).