> Chemokines>Motixafortide TFA(664334-36-5,Free)

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Motixafortide TFA(664334-36-5,Free)

AT14665L

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$99.00

$99.00 per mg

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $44.55 Total: $4,455.00
150 $51.48 Total: $2,574.00
125 $60.39 Total: $1,509.75
110 $71.28 Total: $712.80
15 $84.15 Total: $420.75

Data sheet

Molecular FormulaC99H145F4N33O21S2
Molecular Weight2273.54
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFC(F)(F)C(O)=O.C1C[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2C1)CCCCN)CCCCN)CCCNC(=O)N)CC3=CC=C(C=C3)O)NC(=O)[C@H](CC4=CC5=CC=CC=C5C=C4)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C6=CC=C(C=C6)F)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N)CCCNC(=O)N)CCCNC(=N)N)CC7=CC=C(C=C7)O
ReferencesAbraham M , Klein S , Bulvik B , et al. The CXCR4 inhibitor BL-8040 induces the apoptosis of AML blasts by downregulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a16-1 expression[J]. Leukemia, 2017, 31[11] 2336-2346.

More info

Motixafortide TFA(664334-36-5,Free) (BKT140 TFA) is an antagonist of CXCR4 with IC50 of ?1 nM. It induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a16-1 expression.