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Chemokines
- Protein Control Ligand
- Pathway Inhibitors
- Enzyme Inhibitors
- Kinase Inhibitors
- Protease
- Synthase
- p18
- p38
- p53
- p70
- p90
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- Adenosine Deaminase
- Clathrin
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- p68
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- AChE
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- Autophagy
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- Motilin Receptors
- Muscarinic Receptor
- Neuropeptide Receptors
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- Purinergic Receptors
- Ryanodine receptor
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- VIP and PACAP Receptors
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- Imidazoline receptor
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- Molecular Glues
- PROTAC Linker
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $29.25 | Total: $2,925.00 |
| 1 | 50 | $33.80 | Total: $1,690.00 |
| 1 | 25 | $39.65 | Total: $991.25 |
| 1 | 10 | $46.80 | Total: $468.00 |
| 1 | 5 | $55.25 | Total: $276.25 |
Data sheet
| Molecular Formula | C92H144N34O21S2 |
| Molecular Weight | 2126.47 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H]N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CSSC[C@@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)NC([C@H](NC([C@@H](NC([C@@H](NC([C@@H]2CCCN2C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC3=CC=C(C=C3)O)=O)CCCNC(N)=O)=O)CCCCN)=O)CCCNC(N)=O)=O)=O)CC4=CC=C(C=C4)O)=O)CCCNC(N)=N)=O)CCCNC(N)=O)=O)=O)CC5=CC6=CC=CC=C6C=C5)=O)CCCNC(N)=N)=O)CCCNC(N)=N.CC(O)=O |
| References | H Tamamura, et al. Development of specific CXCR4 inhibitors possessing high selectivity indexes as well as complete stability in serum based on an anti-HIV peptide T140. Bioorg Med Chem Lett. 2001 Jul 23;11[14] 1897-902. |
More info
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM. TC14012 is also a potent CXCR7 agonist with an EC50 of 350 nM for recruiting ?-arrestin 2 to CXCR7. TC14012 has anti-cancer activity and anti-HIV activity.