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View larger C-021 dihydrochloride
AT10639
CAS 1784252-84-1
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $26.10 | Total: $2,610.00 |
| 1 | 50 | $30.16 | Total: $1,508.00 |
| 1 | 25 | $35.38 | Total: $884.50 |
| 1 | 10 | $41.76 | Total: $417.60 |
| 1 | 5 | $49.30 | Total: $246.50 |
Data sheet
| Molecular Formula | C27H43Cl2N5O2 |
| Molecular Weight | 540.57 |
| CAS Numbers | 1784252-84-1 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cl.COc1cc2nc(nc(NC3CCCCCC3)c2cc1OC)N1CCC(CC1)N1CCCCC1 |
| References | Yokoyama K, et al. Potent and orally bioavailable CCR4 antagonists Synthesis and structure-activity relationship study of 2-aminoquinazolines. Bioorg Med Chem. 2009 Jan 1;17[1] 64-73. |
More info
C-021 dihydrochloride is a potent CCR4 antagonist that effectively inhibits functional chemotaxis in humans and mice, with IC50 values of 140 nM and 39 nM, respectively.