Chemokines

CCR6 inhibitor 1 View larger

CCR6 inhibitor 1

AT10715

CAS 2437547-04-9

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$100.00

$100.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $45.00 Total: $4,500.00
150 $52.00 Total: $2,600.00
125 $61.00 Total: $1,525.00
110 $72.00 Total: $720.00
15 $85.00 Total: $425.00

Data sheet

Molecular FormulaC24H23F3N4O3S
Molecular Weight504.52
CAS Numbers2437547-04-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeNC(=O)c1cc(ccn1)-c1ccc(cc1)S(=O)(=O)[C@H]1CC[C@@H](CC1)Nc1ccc(cn1)C(F)(F)F
ReferencesTawaraishi T, et al. Identification of a novel series of potent and selective CCR6 inhibitors as biological probes. Bioorg Med Chem Lett. 2018 Oct 1;28[18] 3067-3072.

More info

CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively). CCR6 is associated with both autoimmune and non-autoimmune diseases, so CCR6 inhibitor 1 is useful for in vitro and in vivo pathophysiology studies as a small molecule inhibitor of CCR6.