Chemokines

INCB3344 View larger

INCB3344

ATQ0103

CAS 1262238-11-8

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$54.00

$54.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $24.30 Total: $2,430.00
150 $28.08 Total: $1,404.00
125 $32.94 Total: $823.50
110 $38.88 Total: $388.80
15 $45.90 Total: $229.50

Data sheet

Molecular FormulaC29H34F3N3O6
Molecular Weight577.59
CAS Numbers1262238-11-8
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[H][C@@]1(CC[C@](O)(CC1)c1ccc2OCOc2c1)N1C[C@H](NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)[C@H](C1)OCC
ReferencesXue CB, et al. Discovery of INCB3344, a potent, selective and orally bioavailable antagonist of human and murine CCR2. Bioorg Med Chem Lett. 2010 Dec 15;20[24] 7473-8

More info

INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis activity.