Chromatin Modifying Enzymes

LBH-589 (Panobinostat) View larger

LBH-589 (Panobinostat)

AOB87727

CAS No:404950-80-7

Chemical Name: Panobinostat 

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$11.00

$11.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $4.95 Total: $495.00
50 $5.72 Total: $286.00
25 $6.71 Total: $167.75
10 $7.92 Total: $79.20
5 $9.35 Total: $46.75

Data sheet

Molecular FormulaC21H23N3O2
Molecular Weight349.4
CAS Numbers404950-80-7
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity 99% (HPLC)
SynonymLBH589; LBH 589; LBH-589; NVP-LBH589; NVP-LBH 589; Panobinostat; trade name Farydak;
IUPAC/Chemical Name (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide
InChl KeyFPOHNWQLNRZRFC-ZHACJKMWSA-N
InChl CodeInChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+
SMILES CodeO=C(NO)/C=C/C1=CC=C(CNCCC2=C(C)NC3=C2C=CC=C3)C=C1
References1) LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Available from http://www.ncbi.nlm.nih.gov/books/NBK548331/ PubMed PMID: 31643653.

2) Moore DC, Arnall JR, Harvey RD. Incidence and management of adverse events associated with panobinostat in the treatment of relapsed/refractory multiple myeloma. J Oncol Pharm Pract. 2019 Apr;25(3):613-622. doi: 10.1177/1078155218788706. Epub 2018 Jul 31. Review. PubMed PMID: 30060709.

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