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COX
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View larger Indomethacin sodium hydrate
AT22346
CAS 74252-25-8
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Data sheet
| Molecular Formula | C19H21ClNNaO7 |
| Molecular Weight | 433.82 |
| CAS Numbers | 74252-25-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C([O-])CC1=C(N(C2=C1C=C(OC)C=C2)C(C3=CC=C(Cl)C=C3)=O)C.[Na+].O.O.O |
| References | Riendeau D, et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Br J Pharmacol. 1997 May;121[1] 105-17. |
More info
Indomethacin sodium hydrate (Indometacin sodium hydrate) is an orally active, competitive and reversible COX12 inhibitor with potential anti-inflammatory activity in induced migraines, induced gastrointestinal injuries, and may be used in studies of increased intracranial pressure secondary to severe traumatic brain injury and rheumatoid arthritis in adults.