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Loxoprofen sodium View larger

Loxoprofen sodium

AT0463L

CAS 80382-23-6

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$33.00

$33.00 per 10 mg

Data sheet

Molecular FormulaC15H17NaO3
Molecular Weight268.2834
CAS Numbers80382-23-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[Na+].CC(C([O-])=O)C1=CC=C(CC2CCCC2=O)C=C1
ReferencesRiendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004;14[5] 1201-1203.

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Loxoprofen sodium (CS-600) is an effective and oral sodium inhibitor of COX-1 and COX-2 with IC50 of 6.5 and 13.5 ?M, respectively. Loxoprofen sodium works by reducing the synthesis of prostaglandins from arachidonic acid. Loxoprofen sodium has anti-inflammatory and antitumor activity and can be used to treat atherosclerosis.