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View larger Loxoprofen sodium
AT0463L
CAS 80382-23-6
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Data sheet
| Molecular Formula | C15H17NaO3 |
| Molecular Weight | 268.2834 |
| CAS Numbers | 80382-23-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [Na+].CC(C([O-])=O)C1=CC=C(CC2CCCC2=O)C=C1 |
| References | Riendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004;14[5] 1201-1203. |
More info
Loxoprofen sodium (CS-600) is an effective and oral sodium inhibitor of COX-1 and COX-2 with IC50 of 6.5 and 13.5 ?M, respectively. Loxoprofen sodium works by reducing the synthesis of prostaglandins from arachidonic acid. Loxoprofen sodium has anti-inflammatory and antitumor activity and can be used to treat atherosclerosis.