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COX
- Protein Control Ligand
- Pathway Inhibitors
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View larger COX-2-IN-6
AT62061
CAS 2756347-91-6
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $48.45 | Total: $242.25 |
| 1 | 10 | $41.04 | Total: $410.40 |
| 1 | 25 | $34.77 | Total: $869.25 |
| 1 | 50 | $29.64 | Total: $1,482.00 |
| 1 | 100 | $25.65 | Total: $2,565.00 |
Data sheet
| Molecular Formula | C20H27NO6S |
| Molecular Weight | 409.5 |
| CAS Numbers | 2756347-91-6 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(CC(C)(C)O)C1=C(C=C(CO)C(OCCC)=N1)C2=CC=C(S(C)(=O)=O)C=C2 |
| References | Zhang Z, et al. Gut-Restricted Selective Cyclooxygenase-2 [COX-2] Inhibitors for Chemoprevention of Colorectal Cancer. J Med Chem. 2021 Aug 12;64[15] 11570-11596. |
More info
COX-2-IN-6 is a potent, selective, and orally available cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 0.84 ?M and a Ki of 69 nM.COX-2-IN-6 inhibits COX-2-driven PGE2 synthesis with an IC50 of 0.60 ?M.COX-2-IN-6 is used to prevent colorectal cancer. COX-2-IN-6 can be used to prevent colorectal cancer.