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> Nuclear Receptor Ligands>CRFR>4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine

CRFR

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine View larger

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine

AT60126

CAS 2649012-21-3

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $84.15 Total: $420.75
110 $71.28 Total: $712.80
125 $60.39 Total: $1,509.75
150 $51.48 Total: $2,574.00
1100 $44.55 Total: $4,455.00

Data sheet

Molecular FormulaC27H28ClFN2OS
Molecular Weight483.04
CAS Numbers2649012-21-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[C@@H](N(CC#C)C1=NC(=C(C)S1)C2=C(Cl)C=C(OC)C(C)=C2)(CC3CC3)C4=CC(F)=C(C)C=C4
ReferencesDzierba CD, Hartz RA, Bronson JJ. Recent advances in corticotropin-releasing factor receptor antagonists. Annu Rep Med Chem. 2008;43 3

More info

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.