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AMD3100 Octahydrochloride View larger

AMD3100 Octahydrochloride Bulk

AOB33719B

CAS 155148-31-5

Chemical Name: Plerixafor; Mozobil; 1-[[4-(1,4,8,11-Tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane octahydrochloride

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Data sheet

Molecular FormulaC28H62Cl8N8
Molecular Weight794.47
CAS Numbers155148-31-5
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO and Water
Purity98% by HPLC
SynonymPlerixafor; Mozobil
IUPAC/Chemical Name1-[[4-(1,4,8,11-Tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane octahydrochloride
InChl KeyUEUPDYPUTTUXLJ-UHFFFAOYSA-N
SMILES CodeC1(CN3CCCNCCNCCCNCC3)=CC=C(CN2CCCNCCNCCCNCC2)C=C1.Cl.Cl.Cl.Cl.Cl.Cl.Cl.Cl
References1) Bridger et al (1995) Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-tetraazamacrocycles that inhibits HIV replication. Effects of macrocyclic ring size and substituents on the aromatic linker. J.Med.Chem. 38 366 PMID: 7830280

2) Hogaboam et al (2005) The therapeutic potential in targeting CCR5 and CXCR4 receptors in infectious and allergic pulmonary disease. Pharmacol.Ther. 107 314 PMID: 16009428

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