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Natural 5-HT 3 receptor antagonist, reducing inflammatory adipokine secretion and NF-κB/JNK activation, improving adiponectin secretion, and inhibiting serine phosphorylation of IRS-1 receptors of insulin signalling pathway, playing a protective and therapeutic role in cuprizone-induced demyelination, negatively modulating the action of GABA at α1β2γ2L GABA A receptors