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View larger SYK-IN-II
AOB36773
CAS 1345458-66-3
Chemical Name: (S)-7-(1-(tert-Butyl)-1H-pyrazol-4-yl)-N-((3-fluoropiperidin-3-yl)methyl)-1,6-naphthyridin-5-amine
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $58.65 | Total: $293.25 |
| 1 | 10 | $49.68 | Total: $496.80 |
| 1 | 25 | $42.09 | Total: $1,052.25 |
| 1 | 50 | $35.88 | Total: $1,794.00 |
| 1 | 100 | $31.05 | Total: $3,105.00 |
Data sheet
| Molecular Formula | C21H27FN6 |
| Molecular Weight | 382.49 |
| CAS Numbers | 1345458-66-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | SYKINII; SYKIN-II; SYK-INII; SYK-IN-II |
| IUPAC/Chemical Name | (S)-7-(1-(tert-Butyl)-1H-pyrazol-4-yl)-N-((3-fluoropiperidin-3-yl)methyl)-1,6-naphthyridin-5-amine |
| InChl Key | KZHRNYBKXGVNJT-NRFANRHFSA-N |
| InChl Code | InChI=1S/C21H27FN6/c1-20(2,3)28-12-15(11-26-28)17-10-18-16(6-4-9-24-18)19(27-17)25-14-21(22)7-5-8-23-13-21/h4,6,9-12,23H,5,7-8,13-14H2,1-3H3,(H,25,27)/t21-/m0/s1 |
| SMILES Code | F[C@]1(CNC2=C3C=CC=NC3=CC(C4=CN(C(C)(C)C)N=C4)=N2)CNCCC1 |
| References | 1) Philip Kocienski; Asymmetric Fluorination Approach to an SYK Inhibitor; Synfacts 11-1011 (2015). DOI: 10.1055/s-0035-1560258 |
More info
Novel inhibitor of the Syk kinase (spleen tyrosine kinase)