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Pim-in-72 View larger

Pim-in-72

AOB11743

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Less active enantiomer of LGH447 (AOB37522), acting as a selective weak pan-PIM inhibitor (IC 50 (µM): PIM1 0.095; PIM2 0.522; PIM3 0.369) in comparision with LGH447 (IC 50 (µM): PIM1 0.001; PIM2 0.002; PIM3 0.002)