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Ac-calpastatin (184-210) View larger

Ac-calpastatin (184-210)

AOB14071

CAS 123714-50-1

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Selective calpain inhibitor, strongly inhibiting calpain I (Ki = 0.2 nM) and II but not inhibiting papain, trypsin and cathepsin L (Ki = 6 μM), increasing secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio