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5-fu Prodrug 4 View larger

5-fu Prodrug 4

AOB16338

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Novel palladium-activated 5-FU prodrug, being completely innocuous to cells and highly resistant to metabolization by primary hepatocytes and liver S9 fractions (the main metabolic route for 5-FU degradation), and rapidly converted into 5-FU in the presence of a palladium (Pd) source