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Si-w052

AOB16122

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Novel inhibitor of lipopolysaccharide (LPS)-induced tumor necrosis factor (TNF)-α and interleukin (IL)-6 on microglia, exhibiting anti-inflammatory activity through ER-stress-mediated autophagy, significantly inducing the conversion ratio of LC3 II/I and inhibiting LPS-upregulated p-mTOR, thereby restoring impaired autophagy to modulate inflammation