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Vu6001966

AOB16183

CAS 2009052-76-8

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Novel potent and selective mGlu2 inhibitor (mGlu2 IC 50 = 78 nM, mGlu3 IC 50 > 30 μM) with excellent central nervous system (CNS) penetration (K p = 1.9, K p,uu = 0.78)