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Parp1/brd4 Inhibitor Iii-7 View larger

Parp1/brd4 Inhibitor Iii-7

AOB16234

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Novel highly selective dual PARP1/BRD4 inhibitor (PARP1 IC 50 =49nM; BRD4 IC 50 =202nM), repressing the expression and activity of PARP1 and BRD4 to synergistically inhibit the malignant growth of pancreatic cancer cells in vitro and in vivo