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Custom Synthesis
- Protein Control Ligand
- Pathway Inhibitors
- Enzyme Inhibitors
- Kinase Inhibitors
- Protease
- Synthase
- p18
- p38
- p53
- p70
- p90
- Peptidase
- Carboxyl and Decarboxylases
- Ceramide Turnover Enzymes
- Chromatin Modifying Enzymes
- Cyclic Nucleotide Turnover Enzymes
- Glycerophospholipid Turnover Enzymes
- Hydroxylases
- Ubiquitin-Activating Enzyme
- Adenosine Deaminase
- Clathrin
- Nuclease
- p68
- ACE
- COX
- DHFR
- Neprilysin
- NF-κB
- RAF
- RAS
- Reductase
- ROR
- Topoisomerase
- Transferase
- Protein Inhibitors
- Transporter Inhibitors
- Cell Inhibition
- Synthase
- Receptor Tyrosine Phosphatases (RTP)
- AChE
- Peptidase
- Autophagy
- Toll-Like Receptor (TLR)
- Enzyme Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- 5HT Receptors
- Adrenoceptor
- Angiotensin Receptor
- Cannabinoid Receptors
- CCK Receptors
- DA Receptors
- EAA Receptors
- Ghrelin Receptors
- GABA Receptors
- Histamine Receptors
- Leukotriene Receptors
- Metabotropic Glutamate Receptors
- Motilin Receptors
- Muscarinic Receptor
- Neuropeptide Receptors
- Opioid Receptors
- Orexin Receptors
- Orphan Receptors
- Prostanoid Receptors
- Proteinase-Activated Receptors
- Purinergic Receptors
- Ryanodine receptor
- Sigma Receptors
- Thrombin Receptor
- Vaniloid Receptor
- VIP and PACAP Receptors
- Neurotensin Receptors
- Urotensin Receptor
- Imidazoline receptor
- SMO Receptors
- Apelin Receptor
- β-arrestin/β2-adaptin
- KDM4
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- Amylin Receptor
- Bombesin Receptor
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- CFTR
- CGRP Receptor
- CRFR
- Endothelin Receptor
- Ephrin Receptor
- Farnesoid X receptor (FXR)
- Glucagon Receptor
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
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- Customized Screening Library
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $26.55 | Total: $2,655.00 |
| 1 | 50 | $30.68 | Total: $1,534.00 |
| 1 | 25 | $35.99 | Total: $899.75 |
| 1 | 10 | $42.48 | Total: $424.80 |
| 1 | 5 | $50.15 | Total: $250.75 |
Data sheet
| Molecular Formula | C15H12N4O |
| Molecular Weight | 264.28 |
| CAS Numbers | 606096-88-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | QN 519; QN-519 |
| IUPAC/Chemical Name | 5-Methyl-N-(8-quinolinyl)-2-pyrazinecarboxamide |
| InChl Key | GCOOYPQZOTUDRJ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C15H12N4O/c1-10-8-18-13(9-17-10)15(20)19-12-6-2-4-11-5-3-7-16-14(11)12/h2-9H,1H3,(H,19,20) |
| SMILES Code | CC1=CN=C(C=N1)C(=O)NC2=CC=CC3=C2N=CC=C3 |
| References | 1) Kuang, Y., et al., Induction of Genes Implicated in Stress Response and Autophagy by a Novel Quinolin-8-yl-nicotinamide QN523 in Pancreatic Cancer; J. Med. Chem. 2022, 65, 8, 6133–6156 |
More info
Novel stress response and autophagy inducer, showing potent in vitro cytotoxicity in a panel of 12 cancer cell lines