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Sirt7 Inhibitor 97491 View larger

Sirt7 Inhibitor 97491

AOB16510

CAS 1807758-81-1

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Novel potent SIRT7 inhibitor with an IC 50 of 325 nM, reducing deacetylase activity of SIRT7 in a dose-dependent manner, preventing tumor progression by increasing p53 stability through acetylation at K373/382, promoting apoptosis through caspase pathway