DA Receptors

JNJ-37822681 dihydrochloride View larger

JNJ-37822681 dihydrochloride

AT11722

CAS 2108806-02-4

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$48.00

$48.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.60 Total: $2,160.00
150 $24.96 Total: $1,248.00
125 $29.28 Total: $732.00
110 $34.56 Total: $345.60
15 $40.80 Total: $204.00

Data sheet

Molecular FormulaC17H19Cl2F5N4
Molecular Weight445.26
CAS Numbers2108806-02-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Cl.Fc1ccc(CN2CCC(CC2)Nc2ccc(nn2)C(F)(F)F)cc1F
ReferencesLanglois X, et al. Pharmacology of JNJ-37822681, a specific and fast-dissociating D2 antagonist for the treatment of schizophrenia. J Pharmacol Exp Ther. 2012 Jul;342[1] 91-105.

More info

JNJ-37822681 dihydrochloride is a novel, highly selective dopamine D? receptor antagonist characterized by a rapid dissociation rate from the dopamine D? receptor. JNJ-37822681 dihydrochloride shows a moderate binding affinity for the dopamine D2L receptor with a Ki of 158 nM.