DA Receptors

6-Chloromelatonin View larger

6-Chloromelatonin

AT22530

CAS 63762-74-3

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$298.00

$298.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $134.10 Total: $13,410.00
150 $154.96 Total: $7,748.00
125 $181.78 Total: $4,544.50
110 $214.56 Total: $2,145.60
15 $253.30 Total: $1,266.50

Data sheet

Molecular FormulaC13H15ClN2O2
Molecular Weight266.72
CAS Numbers63762-74-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(CNC(C)=O)C=1C=2C(=CC(Cl)=C(OC)C2)NC1
ReferencesBrowning C, et al. Pharmacological characterization of human recombinant melatonin mt[1] and MT[2] receptors. Br J Pharmacol. 2000;129[5] 877-886.

More info

6-Chloromelatonin is a potent melatonin receptor agonist, a 5-methoxyindole compound that competes for presynaptic melatonin receptor sites in the rabbit retina, inhibiting the calcium-dependent release of [3H]dopamine with higher metabolic stability than melatonin. Chloromelatonin competitively binds to [3H]melatonin at MT2 receptors (pKi=9.77) and may be used to study insomnia and sleep disorders associated with depression.