EAA Receptors

JNJ-56022486 View larger

JNJ-56022486

AOB31959

CAS: 2036082-79-6

 

Chemical Name: 2-(3-Chloro-2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)phenyl)acetonitrile

 

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$37.50

$37.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $16.88 Total: $1,687.50
150 $19.50 Total: $975.00
125 $22.88 Total: $571.88
110 $27.00 Total: $270.00
15 $31.88 Total: $159.38

Data sheet

Molecular FormulaC15H10ClN3O
Molecular Weight283.72
CAS Numbers2036082-79-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymJNJ-56022486; JNJ 56022486; JNJ56022486
IUPAC/Chemical Name2-(3-chloro-2-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)phenyl)acetonitrile
InChl KeyWJCNWFPRVRWFCU-UHFFFAOYSA-N
InChl CodeInChI=1S/C15H10ClN3O/c16-11-3-1-2-9(6-7-17)14(11)10-4-5-12-13(8-10)19-15(20)18-12/h1-5,8H,6H2,(H2,18,19,20)
SMILES CodeN#CCC1=CC=CC(Cl)=C1C2=CC=C(C(N3)=C2)NC3=O
References1) Maher MP, Ameriks MK, Savall BM, Carruthers NI, Lovenberg TW. Reply to "A Comment on 'Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8'". J Pharmacol Exp Ther. 2016 Sep;358(3):527.

2) Witkin JM, Gardinier KM. A Comment on "Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8". J Pharmacol Exp Ther. 2016 Sep;358(3):502-3.

More info

A novel potent and selective negative modulator of AMPA receptors containing TARP-gamma8