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VU-29
AOB1473
CAS: 890764-36-0
Chemical Name: DPAP; U29; N-(1,3-Diphenyl-1H-pyrazol-5-yl)-4-nitrobenzamide; N-(2,5-Diphenyl-2H-pyrazol-3-yl)-4-nitro-benzamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $6.75 | Total: $675.00 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 5 | $12.75 | Total: $63.75 |
Data sheet
| Molecular Formula | C22H16N4O3 |
| Molecular Weight | 384.39 |
| CAS Numbers | 890764-36-0 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | VU29; VU-29 |
| IUPAC/Chemical Name | N-(1,3-Diphenyl-1H-pyrazolo-5-yl)-4-nitrobenzamide |
| InChl Key | KIALCSMRIHRFPL-UHFFFAOYSA-N |
| SMILES Code | O=C(C4=CC=C([N+]([O-])=O)C=C4)NC1=CC(C3=CC=CC=C3)=NN1C2=CC=CC=C2 |
| References | 1) Chen et al (2007) Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses. Mol.Pharmacol. 71 1389 PMID: 17303702 2) de Paulis et al (2006) Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes. J.Med.Chem. 49 3332 PMID: 16722652 3) Ayala et al (2009) mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning. Neuropsychopharmacology 34 2057 PMID: 19295507 |
| PubChem ID | 11610682 |
More info
Potent noncompetitive antagonist of metabotropic glutamate receptor 5 (mGlu5)