EAA Receptors

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CDPPB

AOB1083

CAS: 781652-57-1

 

Chemical Name: 3-Cyano-N-1,3-diphenyl-1H-pyrazol-5-yl)benzamide

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $6.75 Total: $675.00
150 $7.80 Total: $390.00
125 $9.15 Total: $228.75
110 $10.80 Total: $108.00
15 $12.75 Total: $63.75

Data sheet

Molecular FormulaC23H16N4O
Molecular Weight364.4
CAS Numbers781652-57-1
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical Name3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide Purity: ≥98% (HPLC)
InChl KeyBKUIZWILNWHFHD-UHFFFAOYSA-N
SMILES CodeO=C(C4=CC(C#N)=CC=C4)NC1=CC(C3=CC=CC=C3)=NN1C2=CC=CC=C2
References1) Lindsley et al (2004) Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides that potentiate receptor function in vivo. J.Med.Chem. 47 5825 PMID: 15537338

2) Kinney et al (2005) A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rats behavioral models. J.Pharmacol.Exp.Ther. 313 199 PMID: 15608073
PubChem ID11245456

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Glutamate metabotropic mGluR5 positive allosteric modulator