EAA Receptors

Ro 25-6981 View larger

Ro 25-6981

AT12758

CAS 169274-78-6

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$41.00

$41.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $18.45 Total: $1,845.00
150 $21.32 Total: $1,066.00
125 $25.01 Total: $625.25
110 $29.52 Total: $295.20
15 $34.85 Total: $174.25

Data sheet

Molecular FormulaC22H29NO2
Molecular Weight339.47
CAS Numbers169274-78-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@@H](CN1CCC(Cc2ccccc2)CC1)[C@@H](O)c1ccc(O)cc1
ReferencesFischer G, et al. Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro. J Pharmacol Exp Ther. 1997 Dec;283[3] 1285-92.

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Ro 25-6981 is a potent and selective activity-dependent NMDA receptors blocker containing the NR2B subunit with IC50s of 0.009 and 52 ?M for cloned receptor subunit combinations NR1CNR2B and NR1CNR2A respectively. Ro 25-6981 can be used in studies about Parkinson's disease.