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EAA Receptors
- Protein Control Ligand
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- Biomarkers and Buffer Solutions
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $13.95 | Total: $1,395.00 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 5 | $26.35 | Total: $131.75 |
Data sheet
| Molecular Formula | C8H9NO4S |
| Molecular Weight | 215.23 |
| CAS Numbers | 518357-51-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C(O)=O)(N)C=1SC(C(O)=O)=CC1C |
| References | Moroni, F., et al.The novel and systemically active metabotropic glutamate 1 [mGlu1] receptor antagonist 3-MATIDA reduces post-ischemic neuronal death.Neuropharmacology. 2002. Neuropharmacology. 42 741-751. |
More info
3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 ?M, rat mGluR-1a). Displays ? 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 ?M), NMDA and GluR (AMPA) (IC50 = 250 ?M). 3-MATIDA act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.