EAA Receptors

ADX88178 View larger

ADX88178

AT4500

CAS 1235318-89-4

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$32.00

$32.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $14.40 Total: $1,440.00
150 $16.64 Total: $832.00
125 $19.52 Total: $488.00
110 $23.04 Total: $230.40
15 $27.20 Total: $136.00

Data sheet

Molecular FormulaC12H12N6S
Molecular Weight272.33
CAS Numbers1235318-89-4
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1sc(Nc2nccc(C)n2)nc1-c1cn[nH]c1
ReferencesFujinaga M, et al. Radiosynthesis and evaluation of 5-methyl-N-[4-[[11]C]methylpyrimidin-2-yl]-4-[1H-pyrazol-4-yl]thiazol-2-amine [[[11]C]ADX88178] as a novel radioligand for imaging of metabotropic glutamate receptor subtype 4 [mGluR4]. Bioorg Med Chem Lett. 2016 Jan 15;26[2] 370-4.

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ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.