EAA Receptors

1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- View larger

1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-

AT60224

CAS 175340-21-3

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $44.55 Total: $4,455.00
150 $51.48 Total: $2,574.00
125 $60.39 Total: $1,509.75
110 $71.28 Total: $712.80
15 $84.15 Total: $420.75

Data sheet

Molecular FormulaC10H12N2O2S
Molecular Weight224.28
CAS Numbers175340-21-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=S1(=O)C=2C(N3[C@](N1)(CCC3)[H])=CC=CC2
ReferencesDesos P , Serkiz B , Morain P , et al. Enantioselective synthesis of a pyrrolo-benzothiadiazine derivative S 18986, a new AMPA receptor positive modulator[J]. Bioorganic & Medicinal Chemistry Letters, 1997, 28[23] no-no.

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1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modulator with EC2 (Concentration that doubles the intensity of the AMPA-induced current) of 35 ?M.