> G Protein-Coupled Receptor Ligands>Endothelin Receptor>IRL-1620 acetate

Endothelin Receptor

IRL-1620 acetate View larger

IRL-1620 acetate

AT15595L

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$161.00

$161.00 per mg

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Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $72.45 Total: $7,245.00
150 $83.72 Total: $4,186.00
125 $98.21 Total: $2,455.25
110 $115.92 Total: $1,159.20
15 $136.85 Total: $684.25

Data sheet

Molecular FormulaC88H121N17O29
Molecular Weight1881
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(O)=O.O=C(O)[C@H](CC1=CNC2=C1C=CC=C2)NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC3=CNC=N3)NC([C@H](C)NC([C@H](CC4=CC=CC=C4)NC([C@H](CC5=CC=C(O)C=C5)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC(CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
ReferencesBriyal S, et al. Stimulation of endothelin B receptors by IRL-1620 decreases the progression of Alzheimer's disease. Neuroscience. 2015 Aug 20;301 1-11.

More info

IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 ?M.