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Fidarestat
AOB8310
CAS: 136087-85-9
Chemical Name: Aldos; SNK-860; (2S,4S)-6-Fluoro-2',5'-dioxospiro[2,3-dihydrochromene-4,4'-imidazolidine]-2-carboxamide
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $12.15 | Total: $1,215.00 |
| 1 | 50 | $14.04 | Total: $702.00 |
| 1 | 25 | $16.47 | Total: $411.75 |
| 1 | 10 | $19.44 | Total: $194.40 |
| 1 | 5 | $22.95 | Total: $114.75 |
Data sheet
| Molecular Formula | C12H10FN3O4 |
| Molecular Weight | 279.23 |
| CAS Numbers | 136087-85-9 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (2S,4S)-6-fluoro-2',5'-dioxospiro[chromane-4,4'-imidazolidine]-2-carboxamide |
| InChl Key | WAAPEIZFCHNLKK-UFBFGSQYSA-N |
| InChl Code | InChI=1S/C12H10FN3O4/c13-5-1-2-7-6(3-5)12(4-8(20-7)9(14)17)10(18)15-11(19)16-12/h1-3,8H,4H2,(H2,14,17)(H2,15,16,18,19)/t8-,12-/m0/s1 |
| SMILES Code | O=C([C@@H]1C[C@@](NC2=O)(C(N2)=O)C3=C(O1)C=CC(F)=C3)N |
| References | 1) Pandey S. Aldose Reductase Inhibitor Fidarestat as a Promising Drug Targeting Autophagy in Colorectal Carcinoma: a Pilot Study. Asian Pac J Cancer Prev. 2015;16(12):4981-5. PubMed PMID: 26163626. 2) Talluri MV, et al. LC-MS-MS Characterization of Forced Degradation Products of Fidarestat, a Novel Aldose Reductase Inhibitor: Development and Validation of a Stability-Indicating RP-HPLC Method. J Chromatogr Sci. 2015 Oct;53(9):1588-96. 3) Borkar RM, et al Plasma protein binding, pharmacokinetics, tissue distribution and CYP450 biotransformation studies of fidarestat by ultra high performance liquid chromatography-high resolution mass spectrometry. J Pharm Biomed Anal. 2015 Jan;102:386-99. |
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Aldose reductase inhibitor